The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

Jan. 22, 2014
Applicant:

University of Massachusetts Medical School, Boston, MA (US);

Inventors:

Gang Han, Shrewsbury, MA (US);

Jie Shen, Worcester, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); G01N 21/64 (2006.01); C09K 11/02 (2006.01); C09K 11/77 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); C09K 11/02 (2013.01); C09K 11/025 (2013.01); C09K 11/7773 (2013.01); G01N 21/6486 (2013.01); G01N 2021/6439 (2013.01); G01N 2458/30 (2013.01); G01N 2458/40 (2013.01); Y10T 436/143333 (2015.01);
Abstract

The invention generally relates to materials and methods for creating and/or utilizing upconverting luminescence. More particularly, the invention relates to novel compositions (e.g., nanoparticles) and related methods of preparation and use that enable upconverting luminescence with an efficient excitation optimized at about 800 nm. A unique class of cascade sensitized tri-doped UCNPs with a biocompatible 800 nm excitable property are disclosed herein, for example, tri-doped β-NaYF:Nd,Yb,Er(Tm)/NaYFUCNPs, which employ Ndas 800 nm photon sensitizer and Ybas bridging ions, having strong green or blue upconversion emissions without photobleaching.


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