The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Sep. 23, 2015
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Benjamin Flusberg, Atlanta, GA (US);
Jonas Korlach, Camas, WA (US);
Jeffrey Wegener, Cupertino, CA (US);
Tyson A. Clark, Menlo Park, CA (US);
Igor Drasko Vilfan, East Palo Alto, CA (US);
Andrey Kislyuk, San Ramon, CA (US);
Stephen Turner, Seattle, WA (US);
Jon Sorenson, Alameda, CA (US);
Kevin Travers, Menlo Park, CA (US);
Cheryl Heiner, La Honda, CA (US);
Austin B. Tomaney, Burlingame, CA (US);
Patrick Marks, San Francisco, CA (US);
Jessica Lee, Cupertino, CA (US);
Lei Jia, Newbury Park, CA (US);
Dale Webster, San Mateo, CA (US);
John Lyle, Fremont, CA (US);
Jeremiah Hanes, Menlo Park, CA (US);
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Abstract
Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.