The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Jan. 16, 2014
Applicant:
Nabsys 2.0 Llc, Providence, RI (US);
Inventor:
John S. Oliver, Bristol, RI (US);
Assignee:
NABSYS 2.0 LLC, Providence, RI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/6825 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6858 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6825 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6858 (2013.01); C12Q 1/6869 (2013.01);
Abstract
Methods for enhancing the binding of oligonucleotide probes to DNA and RNA are disclosed. The methods make use of thermodynamic and kinetic effects to reduce probe mismatches and failure of complementary probes to bind to DNA and RNA templates. Mapping and sequencing of the probed DNA and RNA samples are contemplated herein.