The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Apr. 28, 2017
Applicant:
Omniome, Inc., San Diego, CA (US);
Inventors:
Pinar Iyidogan, San Diego, CA (US);
Kandaswamy Vijayan, San Diego, CA (US);
Assignee:
OMNIOME, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6809 (2018.01); C12Q 1/6816 (2018.01); C12Q 1/6848 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6874 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6809 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6848 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01);
Abstract
Provided are methods and systems for detecting formation of nucleotide-specific ternary complexes comprising a DNA polymerase, a nucleic acid, and a nucleotide complementary to the templated base of the primed template nucleic acid. The methods and systems facilitate determination of the next correct nucleotide without requiring chemical incorporation of the nucleotide into the primer. These results can even be achieved in procedures employing unlabeled, native nucleotides.