The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

May. 12, 2017
Applicant:

Lanzatech, Inc., Skokie, IL (US);

Inventors:

Fungmin Liew, Skokie, IL (US);

Michael Koepke, Skokie, IL (US);

Assignee:

LanzaTech, Inc., Skokie, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12P 7/06 (2006.01); C12P 7/64 (2006.01); C12P 5/00 (2006.01); C12P 5/02 (2006.01);
U.S. Cl.
CPC ...
C12P 7/065 (2013.01); C12N 1/20 (2013.01); C12P 5/007 (2013.01); C12P 5/026 (2013.01); C12P 7/6436 (2013.01); C12Y 101/01001 (2013.01); C12Y 102/0101 (2013.01); C12Y 102/07005 (2013.01); Y02E 50/17 (2013.01);
Abstract

The invention provides a non-naturally occurring bacterium having decreased or eliminated activity of an enzyme that catalyzes the reaction defined by EC 1.2.7.5, such as aldehyde:ferredoxin oxidoreductase (AOR). Optionally, the bacterium also has decreased or eliminated activity of an enzyme that catalyzes the reaction defined by EC 1.2.1.10 and/or EC 1.1.1.1, such as aldehyde dehydrogenase, alcohol dehydrogenase, or bifunctional aldehyde/alcohol dehydrogenase. The invention further provides methods of producing products by culturing the bacterium in the presence of a gaseous substrate containing one or more of CO, CO, and H.


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