The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

Mar. 25, 2014
Applicant:

Kaneka Corporation, Osaka, JP;

Inventors:

Misato Matsui, Takasago, JP;

Noriyuki Ito, Takasago, JP;

Shigeru Kawano, Takasago, JP;

Yoshihiko Yasohara, Takasago, JP;

Assignee:

KANEKA CORPORATION, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12Q 1/26 (2006.01); C12N 9/04 (2006.01); C12P 7/02 (2006.01); C12P 7/04 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12P 7/02 (2013.01); C12P 7/04 (2013.01); C12Y 101/01184 (2013.01);
Abstract

An object of the present invention is to modify a wild-type enzyme that is less reactive in the presence of an organic solvent to provide altered carbonyl reductases having better reactivity in the presence of the organic solvent than the wild-type enzyme, and/or to provide transformants producing such reductases. The present inventors have found altered carbonyl reductases having better reactivity in the presence of an organic solvent than the wild-type enzyme, from among a mutant enzyme library prepared by randomly mutating the wild-type enzyme gene, thereby arriving at completion of the present invention.


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