The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

Jun. 21, 2016
Applicant:

Evonik Röhm Gmbh, Darmstadt, DE;

Inventors:

Andreas Kirchner, Andernach, DE;

Rosario Lizio, Dieburg, DE;

Markus Rolf Rossmeissl, Darmstadt, DE;

Wolfgang Luley, Griesheim, DE;

Johannes Vorholz, Alzenau, DE;

Silko Grimm, Rossdorf, DE;

Marc Schneider, Saarbruecken, DE;

Assignee:

Evonik Röhm GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); C08J 3/09 (2006.01); C08J 3/12 (2006.01); A61K 47/34 (2017.01); C08G 63/88 (2006.01);
U.S. Cl.
CPC ...
C08J 3/12 (2013.01); A61K 9/146 (2013.01); A61K 47/34 (2013.01); C08G 63/88 (2013.01); C08J 3/095 (2013.01); C08J 2367/04 (2013.01);
Abstract

A process for preparing poly(lactide-co-glycolide) copolymer particles with an average particle size in the range of 50-800 nm includes transferring a mixture of poly(lactide-co-glycolide) copolymer, ethanol and carbon dioxide from a first reactor into a second reactor under rapid reduction of the pressure and expansion with phase separation into a gas phase, an ethanol aerosol and an ethanolic suspension containing poly(lactide-co-glycolide) copolymer particles, removing the carbon dioxide gas and the ethanol aerosol from the second reactor, and obtaining the poly(glycolide-co-lactide) copolymer particles in the form of an ethanolic suspension or in dry form from the second reactor.


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