The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Mar. 25, 2014
Applicant:
The Pirbright Institute, Pirbright, Woking, GB;
Inventors:
Abhay Kotecha, Oxford, GB;
David Stuart, Oxford, GB;
Elizabeth Fry, Oxford, GB;
Robert Esnouf, Oxford, GB;
Assignee:
The Pirbright Institute, Pirbright, Woking, Surrey, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 5/00 (2006.01); A61K 39/25 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 39/135 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61K 39/135 (2013.01); C12N 7/00 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/552 (2013.01); C12N 2770/32122 (2013.01); C12N 2770/32123 (2013.01); C12N 2770/32134 (2013.01); C12N 2770/32151 (2013.01);
Abstract
The present invention relates to the stabilization of foot-and-mouth disease virus (FMDV) capsids, by specific substitution of amino acids in a specific region of FMDV VP2. The invention provides stabilized FMDV capsids and vaccines against FMD.