The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Apr. 01, 2015
Applicant:
University of Rochester, Rochester, NY (US);
Inventor:
Rudi Fasan, Rochester, NY (US);
Assignee:
University of Rochester, Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 7/54 (2006.01); A61K 38/00 (2006.01); A61K 38/12 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/54 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/001 (2013.01); A61K 38/00 (2013.01); A61K 38/12 (2013.01);
Abstract
Methods and compositions are provided for generating macrocyclic peptides constrained by side-chain-to-C-terminus non-peptidic tethers for use as functional and structural mimics of α-helical motifs, including in therapeutic applications. These methods can be used to produce libraries of conformationally constrained peptidomimetics to identify compounds with desired activity properties.