The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Jun. 21, 2016
Sumitomo Dainippon Pharma Co., Ltd., Osaka, JP;
Hitoshi Ban, Osaka, JP;
Manabu Kusagi, Osaka, JP;
Yosuke Takanashi, Osaka, JP;
Futoshi Hasegawa, Osaka, JP;
Sumitomo Dainippon Pharma Co., Ltd., Osaka, JP;
Abstract
The present invention provides a bicyclic heterocyclic amide derivative of formula (1) wherein ring Qis optionally-substituted Caryl group, etc.; Rand Rare independently hydrogen atom, etc.; Wis optionally-substituted Calkylene group; Wis —NRC(O)—, etc. wherein Ris hydrogen atom or Calkyl group; Cyis the following group of formula (11), etc.; ring Qis optionally-substituted benzene ring, etc.; n and m are independently 0, 1 or 2, provided that n and m are not simultaneously 0; X is NR, etc.; Ris hydrogen atom, etc.; p is 1, 2, 3, 4 or 5; Ris, independently when two or more exist, hydrogen atom, etc.; and a pharmacologically acceptable salt thereof, which have a potent inhibitory effect on the sphere-forming ability of cancer cells and are useful as an orally-available anti-tumor agent.