The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

Apr. 15, 2016
Applicant:

University Court of the University of Edinburgh, Edinburgh, GB;

Inventors:

Asier Unciti-Broceta, Edinburgh, GB;

Craig Fraser, Edinburgh, GB;

Neil O. Carragher, Edinburgh, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01); A61P 43/00 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01); A61P 43/00 (2018.01); C07D 519/00 (2013.01); C12Q 1/485 (2013.01); Y02A 50/385 (2018.01);
Abstract

A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, (Formula (I)) wherein: Ris (CH)NRR; Ris selected from H, halo, OR, NHR, alkyl, alkenyl and alkynyl; Ris selected from alkyl, alkenyl, alkynyl, aryl, halo, aryloxy, NHCOR, NHCONRR, NHCOR, NH-alkyl, NH-alkenyl, NH(CH);-aryl, (CH)-heteroaryl, (CH)COR, (CH)CORand NHSOR, wherein each alkyl, alkenyl, aryl or heteroaryl moiety in the aforementioned list is optionally further substituted by one or more groups selected from alkyl, halo OH, NH, alkoxy, aryloxy, alkylamino, arylamino, carboxyl and carboxamide; Rto Rand Rare each independently selected from alkyl, alkenyl and aryl; Rand Rare each independently selected from alkyl and alkenyl; or Rand R:are linked together with the nitrogen to which they are attached to form a heterocycloalkyl or heterocycloalkenyl group; n, m, p, q and r are each independently selected from 0, 1, 2, 3, 4, 5 and 6. Further aspects relate to pharmaceutical compositions, therapeutic uses and process for preparing according to the invention.


Find Patent Forward Citations

Unciti-Broceta, Asier. (2019). Compounds (U.S. Patent No. 10294227). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10294227

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