The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Oct. 04, 2017
Curadev Pharma Private Ltd., Noida, IN;
Monali Banerjee, Greater Noida, IN;
Sandip Middya, Greater Noida, IN;
Ritesh Shrivastava, Greater Noida, IN;
Sushil Raina, Noida, IN;
Arjun Surya, New Delhi, IN;
Dharmendra B. Yadav, Noida, IN;
Veejendra K. Yadav, Kanpur, IN;
Kamal Kishore Kapoor, Jammu, IN;
Aranapakam Venkatesan, Rego Park, NY (US);
Roger A. Smith, Chester Springs, PA (US);
Scott K. Thompson, Phoenixville, PA (US);
CURADEV PHARMA, PVT. LTD., New Delhi, IN;
Abstract
The present application provides novel inhibitors of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxygenase, metabolites thereof, and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. A therapeutically effective amount of one or more of the compounds of formula (I) is useful in treating diseases resulting from dysregulation of the kynurenine pathway. Compounds of formula (I) act by inhibiting the enzymatic activity or expression of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxy-genase.