The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

Jan. 04, 2017
Applicant:

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Charlotte Hauser, Singapore, SG;

Wei Yang Seow, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A01N 25/00 (2006.01); A01N 47/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); A61L 27/38 (2006.01); A61K 47/42 (2017.01); A61K 38/02 (2006.01); A61L 27/22 (2006.01); A61L 27/50 (2006.01); A61L 27/52 (2006.01); A61L 26/00 (2006.01); A61K 9/06 (2006.01); A61K 35/33 (2015.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61L 27/3804 (2013.01); A61K 9/06 (2013.01); A61K 35/33 (2013.01); A61K 38/02 (2013.01); A61K 47/42 (2013.01); A61L 26/008 (2013.01); A61L 26/0028 (2013.01); A61L 26/0061 (2013.01); A61L 27/22 (2013.01); A61L 27/38 (2013.01); A61L 27/50 (2013.01); A61L 27/52 (2013.01); C12N 5/0018 (2013.01); C12N 5/0062 (2013.01); C12N 5/0068 (2013.01); C12N 5/0671 (2013.01); C12N 5/0691 (2013.01); A61L 2300/412 (2013.01); A61L 2300/426 (2013.01); A61L 2400/06 (2013.01); A61L 2430/00 (2013.01); A61L 2430/06 (2013.01); A61L 2430/38 (2013.01); C12N 2513/00 (2013.01); C12N 2533/50 (2013.01); C12N 2533/54 (2013.01); C12N 2537/10 (2013.01);
Abstract

The present invention relates to hydrogels comprising a plurality of amphiphilic peptides and/or peptoids capable of self-assembling into three-dimensional macromolecular nanofibrous networks, which entrap water and form said hydrogels, wherein at least a portion of said plurality of amphiphilic peptides is chemically cross-linked. The present invention further relates to methods for preparing such hydrogels and to various uses of such hydrogels, e.g. as cell culture substrates, for drug and gene delivery, as wound dressing, as an implant, as an injectable agent that gels in situ, in pharmaceutical or cosmetic compositions, in regenerative medicine, in tissue engineering and tissue regeneration, or in electronic devices. It also relates to a method of tissue regeneration or tissue replacement using a hydrogel in accordance with the present invention.


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