The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Jul. 23, 2015
Applicant:
Clemson University, Clemson, SC (US);
Inventors:
Leslie Sierad, Central, SC (US);
Eliza Laine Shaw, Georgetown, SC (US);
George Fercana, Florence, SC (US);
Dan Simionescu, Pendleton, SC (US);
Assignee:
Clemson University Research Foundation, Clemson, SC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/24 (2006.01); A61L 27/36 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3687 (2013.01); A61L 27/3604 (2013.01); A61L 27/3625 (2013.01); A61L 27/3691 (2013.01); A61F 2/2415 (2013.01); A61L 2430/20 (2013.01); A61L 2430/40 (2013.01);
Abstract
Systems and methods that establish a pressure differential across a tissue wall to encourage complete decellularization of the wall are described. The methods can be utilized for decellularization of blood vessel tissue including heart valves and surrounding tissues. The methods and systems can essentially completely decellularize the treated tissue segments. Systems can be utilized to decellularize one or multiple tissue segments at a single time.