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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10292943 B1

PDFFull Text
Date of Patent:
May. 21, 2019

Filed:

Aug. 10, 2015

Delivery of bioactive, nanoencapsulated antioxidants

Applicants:

Cristina M. Sabliov, Baton Rouge, LA (US);

Carlos E. Astete, Baton Rouge, LA (US);

Ede Bodoki, Cluj-Napoca, RO;

Oliviu Vostinaru, Cluj-Napoca, RO;

Ovidiu Ciprian Samoil{hacek Over (A)}, Cluj-Napoca, RO;

Elena Dinte, Cluj-Napoca, RO;

Inventors:

Cristina M. Sabliov, Baton Rouge, LA (US);

Carlos E. Astete, Baton Rouge, LA (US);

Ede Bodoki, Cluj-Napoca, RO;

Oliviu Vostinaru, Cluj-Napoca, RO;

Ovidiu Ciprian Samoil{hacek over (a)}, Cluj-Napoca, RO;

Elena Dinte, Cluj-Napoca, RO;

Assignee:

Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US);

Attorney:

John H. Runnels

Primary Examiner:

Aradhana Sasan

Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01); A61K 31/05 (2006.01); A61K 47/10 (2017.01); A61K 47/24 (2006.01); A61K 47/34 (2017.01); A61P 27/12 (2006.01); A61K 31/047 (2006.01);
U.S. Cl.
CPC ...
A61K 31/047 (2013.01); A61K 9/0048 (2013.01); A61K 9/06 (2013.01); A61K 9/5146 (2013.01); A61K 9/5153 (2013.01); A61K 9/5169 (2013.01); A61K 9/5192 (2013.01); A61K 31/05 (2013.01); A61K 47/10 (2013.01); A61K 47/24 (2013.01); A61K 47/34 (2013.01); A61P 27/12 (2018.01); A61K 9/0051 (2013.01); A61K 9/19 (2013.01);
Abstract

Methods and compositions are disclosed for delivering lutein or other antioxidant to target tissues such as the eye, in bioactive form, while protecting the antioxidant from degradation. The antioxidant is encapsulated in nanoparticles comprising a protein such as zein or a polymer such as poly(lactic-co-glycolic acid) (PLGA). Preferably a surfactant is associated with the nanoparticles as well, further helping to protect the antioxidant. After the nanoparticles are administered to the target tissue, bioactive antioxidant is released to the tissue over time. Optionally, the nanoparticles are admixed with a thermosensitive, bioadhesive gel to promote slow release of antioxidant. The methods and compositions are useful for treating or preventing conditions such as age-related macular degeneration or cataracts.

Find Patent Forward Citations

Sabliov, Cristina. (2019). Delivery of bioactive, nanoencapsulated antioxidants (U.S. Patent No. 10292943). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10292943

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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