The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2019

Filed:

Apr. 25, 2016
Applicant:

Samyang Biopharmaceuticals Corporation, Seoul, KR;

Inventors:

Se-Ho Kim, Daejeon, KR;

Ji-Yeon Son, Gimhae, KR;

Muhn-Ho La, Daejeon, KR;

Sung-Won Choi, Daejeon, KR;

Min-Hyo Seo, Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); C12N 15/11 (2006.01); A61K 9/107 (2006.01); A61K 31/7105 (2006.01); A61K 9/127 (2006.01); A61K 47/24 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 9/1271 (2013.01); A61K 31/7105 (2013.01); A61K 47/24 (2013.01); A61K 47/34 (2013.01); C12N 15/111 (2013.01); A61K 9/0019 (2013.01); C12N 15/11 (2013.01); C12N 2320/32 (2013.01);
Abstract

Disclosed are an anionic drug-containing polymeric micelle particle comprising: an anionic drug as an active ingredient; a cationic lipid; and an amphiphilic block copolymer, wherein the anionic drug forms a complex with the cationic lipid, and the complex is entrapped in the micelle structure of the amphiphilic block copolymer, and a method for preparing the same. The particle may increase stability of the anionic drug in blood or in a body fluid, and it may enable intracellular delivery to improve efficacy of anionic drugs.


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