The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2019
Filed:
Nov. 10, 2016
Omeros Corporation, Seattle, WA (US);
George A. Gaitanaris, Seattle, WA (US);
John E. Bergmann, Albany, CA (US);
Alexander Gragerov, Seattle, WA (US);
John Hohmann, Seattle, WA (US);
Fusheng Li, Seattle, WA (US);
Linda Madisen, Seattle, WA (US);
Kellie L. McIlwain, Washington, DC (US);
Maria N. Pavlova, Seattle, WA (US);
Demetri Vassilatis, Seattle, WA (US);
Hongkui Zeng, Seattle, WA (US);
Omeros Corporation, Seattle, WA (US);
Abstract
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.