The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Apr. 19, 2017
Applicant:

University of Central Lancashire, Lancashire, GB;

Inventors:

Matthew James Baker, Lytham St Annes, GB;

Peter Abel, Southport, GB;

Robert William Lea, Preston, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 21/552 (2014.01); G01N 21/63 (2006.01); G01N 21/35 (2014.01); G01N 33/49 (2006.01); G01J 3/433 (2006.01); G01N 30/74 (2006.01); G01N 21/31 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57407 (2013.01); G01N 21/552 (2013.01); G01N 33/49 (2013.01); G01N 33/574 (2013.01); G01J 3/433 (2013.01); G01N 21/35 (2013.01); G01N 21/63 (2013.01); G01N 2021/3196 (2013.01); G01N 2021/3595 (2013.01); G01N 2030/743 (2013.01); G01N 2201/129 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7028 (2013.01);
Abstract

The present invention relates to methods of diagnosing and/or prognosing proliferative disorders, especially brain cancers (e.g. gliomas). In particular, the present invention provides a means to conveniently detect malignant tumors merely by assaying or analyzing blood (particularly blood serum). Cytokines and/or angiogenesis factors in blood serum have been found to be surprisingly powerful at indicating the presence of brain cancers in a subject. Moreover, spectroscopic analysis, especially ATR-FTIR analysis, of a blood sample has been demonstrated to be surprisingly effective at producing a signature that can be correlated with the presence, extent, severity, or aggressiveness of malignant tumors in a subject.


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