The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Feb. 08, 2017
Applicant:

Industry-academic Cooperation Foundation Yonsei University, Seoul, KR;

Inventors:

Sang Yup Lee, Seoul, KR;

Chaemyeong Lee, Gwangju, KR;

Min Chul Kim, Siheung-si, KR;

Jin Young Kwak, Seoul, KR;

Sang Woo Park, Daejeon, KR;

Young Jun Lim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08K 5/29 (2006.01); C08K 5/42 (2006.01); C08J 3/075 (2006.01); G01N 21/77 (2006.01); G01N 21/80 (2006.01);
U.S. Cl.
CPC ...
G01N 21/80 (2013.01); C08J 3/075 (2013.01); C08K 5/29 (2013.01); C08K 5/42 (2013.01); C08J 2305/04 (2013.01); G01N 2021/7763 (2013.01);
Abstract

A method for preparing a hydrogel that reversibly changes color depending on pH includes: (S) dissolving a carboxyl group-containing polysaccharide in buffer to obtain a polysaccharide solution; (S) adding a cross-linker solution composed of a mixture of an organic solvent and a cross-linker to the polysaccharide solution; (S) adding, to the cross-linker-containing polysaccharide solution resulting from step (S), an organic solution composed of a mixture of an organic solvent and a first organic compound containing an aromatic functional group having at least one hydroxyl group bonded thereto, to form a mixture solution, and allowing the mixture solution to react; (S) obtaining a polymer complex from the reaction mixture resulting from step (S); and (S) mixing the polymer complex from step (S) with an organic dye comprising a second organic compound containing an aromatic functional group having at least one hydroxyl group bonded thereto.


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