The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Aug. 07, 2017
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Kenneth Jeffrey Hayworth, Ashburn, VA (US);

Richard Schalek, Wakefield, MA (US);

Juan Carlos Tapia, Bronx, NY (US);

Narayanan Kasthuri, Cambridge, MA (US);

Jeff Lichtman, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/06 (2006.01); A61B 16/00 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
G01N 1/06 (2013.01); A61B 16/00 (2013.01); G01N 35/00009 (2013.01); G01N 2001/061 (2013.01); G01N 2001/065 (2013.01); G01N 2001/066 (2013.01); G01N 2001/068 (2013.01);
Abstract

Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.


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