The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Feb. 06, 2015
Applicant:

Dsm Ip Assets B.v., Heerlen, NL;

Assignee:

DSM IP Assets B.V., Heerlen, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/75 (2006.01); C12N 9/54 (2006.01); C12P 21/02 (2006.01); C12N 9/26 (2006.01); C12N 9/24 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/75 (2013.01); C12N 9/2411 (2013.01); C12N 9/2482 (2013.01); C12N 9/54 (2013.01); C12P 21/00 (2013.01); C12P 21/02 (2013.01); C12Y 302/01008 (2013.01); C12Y 302/01133 (2013.01); C12Y 304/21062 (2013.01); C12Y 304/24028 (2013.01);
Abstract

The invention provideshost cell deficient in the production of a neutral protease and of a alkaline protease which host cell comprises a nucleic acid construct, wherein the nucleic acid construct comprises a polynucleotide encoding a compound of interest or encoding a compound involved in the synthesis of a compound of interest operably linked to a promoter sequence allowing for expression of the polynucleotide in the host cell, wherein the promoter comprises a bacteriophage promoter sequence, more preferably a bacteriophage SPO1 promoter sequence. Said host cell can advantageously be used in a method of production of a compound of interest.


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