The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Aug. 22, 2013
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Shiv Srivastava, Potomac, MD (US);
Albert Dobi, Rockville, MD (US);
Taduru Sreenath, Germantown, MD (US);
Gyorgy Petrovics, Bethesda, MD (US);
Chen Sun, Bethesda, MD (US);
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);
Abstract
The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG.