The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Oct. 31, 2014
Regents of the University of Minnesota, Minneapolis, MN (US);
Benjamin Joseph Hackel, Edina, MN (US);
Max Anthony Kruziki, St. Paul, MN (US);
Sumit Bhatnagar, Ann Arbor, MI (US);
Hong Zhou, Minneapolis, MN (US);
REGENTS OF THE UNIVERSITY OF MINNESOTA, Minneapolis, MN (US);
Abstract
This disclosure describes non-naturally occurring protein scaffolds and methods of making and using the protein scaffolds. In one aspect, therefore, this disclosure describes a non-naturally occurring protein scaffold that includes a plurality of structural domains and a plurality of loop regions that include an amino acid sequence that varies from a naturally-occurring loop region by at least one amino acid deletion, substitution, or addition. Generally, the structural domain or domains can include at least one β structure and/or at least one a helix.