The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Jan. 16, 2017
Applicant:
Butamax Advanced Biofuels Llc, Wilmington, DE (US);
Inventors:
Kristen J. Kelly, Wilmington, DE (US);
Rick W. Ye, Hockessin, DE (US);
Assignee:
Butamax Advanced Biofuels LLC, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12P 7/16 (2006.01); C12P 7/40 (2006.01); B01D 11/04 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); B01D 11/04 (2013.01); C12N 15/52 (2013.01); C12P 7/16 (2013.01); C12P 7/40 (2013.01); C12Y 101/01001 (2013.01); C12Y 101/01086 (2013.01); C12Y 202/01006 (2013.01); C12Y 402/01009 (2013.01); Y02E 50/10 (2013.01); Y02P 20/52 (2015.11);
Abstract
Methods of screening for dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed, along with DHAD variants identified by these methods. Such enzymes can result in increased production of compounds from DHAD requiring biosynthetic pathways. Also disclosed are isolated nucleic acids encoding the DHAD variants, recombinant host cells comprising the isolated nucleic acid molecules, and methods of producing butanol.