The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Apr. 11, 2014
Applicants:

Agency for Science, Technology and Research, Singapore, SG;

Singapore Health Services Pte Ltd, Singapore, SG;

Inventors:

Mei Yee Vanessa Ding, Singapore, SG;

Boon Hwa Andre Choo, Singapore, SG;

Chui Ping Angela Chin, Singapore, SG;

Jodhbir Singh Mehta, Singapore, SG;

Gary Peh, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/12 (2006.01); C12N 5/079 (2010.01); C07K 16/28 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0621 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); C07K 16/40 (2013.01); C07K 2317/33 (2013.01);
Abstract

This invention refers to an antibody or an antigen binding portion thereof, that binds specifically to human corneal endothelial cells (hCENCs), wherein the target of the monoclonal antibody, or antigen binding portion thereof, is essentially cell surface-expressed Peroxiredoxin-6 (Prdx6), as well as to methods for determining suitability of a cell sample for corneal transplantation, for quantitative enrichment of human corneal endothelial cells from a mixture of cells, and for isolating human corneal endothelial cells from a mixture of cell.


Find Patent Forward Citations

Loading…