The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Sep. 18, 2017
Cantargia Ab, Lund, SE;
Helena Ågerstam, Lund, SE;
Thoas Fioretos, Lund, SE;
Marcus Järås, Lund, SE;
Cecilia Ann-Christin Malmborg Hager, Helsingborg, SE;
Kjell Sjöström, Lund, SE;
Agneta Svedberg, Lund, SE;
Karin von Wachenfeldt, Lund, SE;
Cantargia AB, Lund, SE;
Abstract
The present invention provides an antibody or an antigen-binding fragment thereof with binding specificity for human interleukin-1 receptor accessory protein (IL1RAP) wherein the antibody or antigen-binding fragment is capable of inhibiting the binding of antibody 'CAN04' to human IL1RAP. The invention further provides the use of such antibodies or an antigen-binding fragments in the treatment and/or diagnosis of IL-1 associated diseases and conditions, including cancers such as acute myeloid leukemia and melanoma.