The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Apr. 10, 2014
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd, Jerusalem, IL;
Inventors:
Haya Lorberboum-Galski, Jerusalem, IL;
Hagar Greif, Ness Ziona, IL;
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/45 (2006.01); C07K 19/00 (2006.01); C07K 14/16 (2006.01); C07K 14/47 (2006.01); C12N 9/10 (2006.01); C07K 14/435 (2006.01); A61K 9/00 (2006.01); C07K 14/005 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); A61K 9/0019 (2013.01); C07K 14/005 (2013.01); C07K 14/47 (2013.01); C12N 9/1018 (2013.01); A61K 38/00 (2013.01); C07K 2319/07 (2013.01); C07K 2319/10 (2013.01); C07K 2319/21 (2013.01); C12N 2740/16033 (2013.01); C12Y 108/01004 (2013.01); C12Y 203/03001 (2013.01); Y10S 530/826 (2013.01); Y10S 530/827 (2013.01);
Abstract
Disclosed are fusion protein constructs comprising a functional mitochondrial protein, that can enter mitochondria within intact cells. Further disclosed are methods of treating mitochondrial disorders by the disclosed fusion proteins and compositions therefor.