The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Feb. 24, 2017
Applicant:
Kemyth Biotech Co., Ltd., Hsinchu, TW;
Inventors:
Leung-Kei Siu, Taipei, TW;
Pele Choi-Sing Chong, Toronto, CA;
Feng-Yee Chang, Taipei, TW;
Chih-Hsiang Leng, Taipei, TW;
Assignee:
KeMyth Biotech Co., Ltd., Taipei, TW;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/315 (2006.01); A61K 38/00 (2006.01); A61P 29/00 (2006.01); A61P 3/10 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/3156 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to treatment of diabetes, toll-like receptor 4 (TLR-4) modulators and methods for using the same. Particularly, the present invention provides an isolated peptide from pneumolysin (PLY peptide) which is effective in treatment of diabetes. In addition, the PLY peptide of the present invention is a TLR-4 antagonist and thus can be used in the treatment of a disease or condition associated with TLR-4 activation. The present invention also provides treatment of diabetes with a TLR-4 antagonist.