The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Aug. 02, 2018
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Ethan Settembre, Lexington, MA (US);
Angelica Medina-Selby, San Francisco, CA (US);
Doris Coit, Emeryville, CA (US);
Philip R. Dormitzer, Emeryville, CA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01); C12N 7/00 (2006.01); A61K 39/125 (2006.01); A61K 39/295 (2006.01); C07K 14/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61K 39/295 (2013.01); C07K 14/08 (2013.01); C12N 7/00 (2013.01); C07K 2319/00 (2013.01); C12N 2770/16022 (2013.01); C12N 2770/16023 (2013.01);
Abstract
The invention relates to chimeric norovirus VP1 proteins containing the S-domain of VP1 of a first norovirus strain and a P-domain that contains at least a portion of the P-domain of VP1 of a second norovirus strain. The invention also relates to nucleic acids that encode the chimeric VP1 proteins, virus-like particles that contain a chimeric norovirus VP1 protein, and to immunogenic compositions.