The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Feb. 04, 2015
Applicant:

Universitetet I Tromsø—norges Arktiske Universitet, Tromsø, NO;

Inventors:

John Sigurd Svendsen, Kvaløysletta, NO;

Øystein Rekdal, Billingstad, NO;

Johannes Eksteen, Tromsø, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 7/06 (2006.01); A61K 38/03 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C07K 7/06 (2013.01); A61K 38/00 (2013.01); A61K 38/03 (2013.01);
Abstract

The present invention provides a peptide which: (i) consists of 10 to 16 amino acids; (ii) has at least 8 cationic amino acids with either (a) a side chain comprising a guanidinium group, or (b) a side chain comprising an amino group, of which no more than 7 are consecutive; and (iii) has 2 or 3 tryptophan residues which are not both, or not all, consecutive, said peptide optionally in the form of a salt, ester or amide, or a peptidomimetic of said peptide. The invention further relates to pharmaceutical compositions containing these compounds, the use of these compounds in therapy, particularly as anti-tumor (e.g. anti-lymphoma) agents and non-therapeutic uses of these compounds.


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