The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Apr. 28, 2014
Zhejiang Hisun Pharmaceutical Co., Ltd., Zhejiang, CN;
Yanghui Guo, Zhejiang, CN;
Junhui Zhou, Zhejiang, CN;
Qingfeng Cai, Zhejiang, CN;
Hegeng Wei, Zhejiang, CN;
Hua Bai, Zhejiang, CN;
Fei Long, Zhejiang, CN;
Yue Zhang, Zhejiang, CN;
Yingqiu Wu, Zhejiang, CN;
Zhejiang Hisun Pharmaceutical Co., Ltd., Zhejiang, CN;
Abstract
The present invention relates to a disaccharide intermediate and a synthesis method thereof, relates to the chemical pharmaceutical field, and more specifically relates to a method for preparing a disaccharide segment of a key intermediate for chemically synthesizing heparin and heparinoid compounds. Disclosed are a new disaccharide intermediate and three methods for synthesizing the disaccharide intermediate, that is, compounds of a formula (4) and glucopyranose protected by different anomeric carbon are made to react in the presence of an active agent, to obtain the disaccharide intermediate. According to the technical solutions of the present invention, synthetic raw materials are easy to obtain, have a mild reaction condition, and are suitable for industrialized production.