The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Nov. 20, 2017
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Ruoxi Lan, Waltham, MA (US);
Bayard R. Huck, Sudbury, MA (US);
Xiaoling Chen, Chestnut Hill, MA (US);
Yufang Xiao, Lexington, MA (US);
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 498/04 (2006.01); C07D 475/06 (2006.01); C07D 487/04 (2006.01); A61K 31/496 (2006.01); A61K 31/519 (2006.01); A61K 31/5383 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); C07D 239/70 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/496 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/5383 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07D 239/70 (2013.01); C07D 471/04 (2013.01); C07D 475/06 (2013.01); C07D 487/04 (2013.01); A61N 2005/1098 (2013.01);
Abstract
The invention provides novel imidazol-piperidinyl derivatives of the formula (I) in which R, R, W, X, X, X, Xand n have the meanings indicated in formula I, and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.