The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Feb. 19, 2016
The General Hospital Corporation, Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
Klaus Joachin Van Leyen, Medford, MA (US);
Theodore R. Holman, Santa Cruz, CA (US);
David J. Maloney, Point of Rocks, MD (US);
Ajit Jadhav, Chantilly, VA (US);
Anton Simeonov, Santa Cruz, CA (US);
Ganesha Rai, Arlington, VA (US);
THE CHILDREN'S HOSPITAL CORPORATION, Boston, MA (US);
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services, Washington, DC (US);
Abstract
A systematic screening has revealed a family of compounds that exhibit inhibitory effects on 12/15-lipoxygenase. Accordingly, the present invention relates to the use of these compounds for the inhibition of 12/15-lipoxygenase and for the treatment of a condition involving 12/15-lipoxygenase. Exemplary conditions include, but are not limited to, stroke, periventricular leukomalacia, cardiac arrest with resuscitation, atherosclerosis, Parkinson's disease, Alzheimer's disease, and breast cancer.