The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Jul. 10, 2015
Indole compounds having antiprotozoal activity and its use as well as methods for producing the same
Technische Universitaet Braunschweig, Braunschweig, DE;
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Jerusalem, IL;
Conrad Kunick, Hamburg, DE;
Hoang Lande, Braunschweig, DE;
Johann Gruenefeld, Ribbesbuettel, DE;
Ron Dzikowski, Jerusalem, IL;
Abed Nasereddin, Jerusalem, IL;
TECHNISCHE UNIVERSITAET BRAUNSCHWEIG, Braunschweig, DE;
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., Jerusalem, IL;
Abstract
In a first aspect, the present invention relates to new compounds as depicted in formula (I). In particular, compounds according to the present invention are bisindolylcyclobuten-dione-based structures having antiprotozoal activity. In a further aspect, pharmaceutical compositions containing the same are provided as well as the use of the compounds and pharmaceutical compositions for the prophylaxis and treatment of parasite based diseases including malaria. Finally, methods for the treatment of parasite diseases including malaria are provided.