The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2019
Filed:
Jun. 26, 2015
Applicant:
Amphastar Pharmaceuticals Inc., Rancho Cucamonga, CA (US);
Inventors:
Assignee:
Amphastar Pharmaceuticals, Inc., Rancho Cucamonga, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 221/22 (2006.01); C07D 471/12 (2006.01);
U.S. Cl.
CPC ...
C07D 221/22 (2013.01); C07D 471/12 (2013.01);
Abstract
A method of resolving a racemic mixture of (±)-Huperzine A to (−)-Huperzine A includes: separating the (−)-Huperzine A from the racemic mixture of (±)-Huperzine A by chiral high performance liquid chromatography (HPLC), the chiral HPLC being performed utilizing a mobile phase including a solution including an alcohol and one selected from dichloromethane, trichloromethane, and a mixture thereof, and the chiral HPLC being performed utilizing a chiral stationary phase including a polysaccharide derivative.