The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

May. 10, 2018
Applicant:

University of Central Oklahoma, Edmond, OK (US);

Inventors:

Morshed Khandaker, Edmond, OK (US);

Shahram Riahinezhad, Fort Lee, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/30 (2006.01); A61L 24/10 (2006.01); A61F 2/28 (2006.01); A61K 38/18 (2006.01); A61L 24/00 (2006.01); A61L 24/02 (2006.01); A61L 24/06 (2006.01); A61B 17/86 (2006.01); A61B 17/56 (2006.01); A61F 2/36 (2006.01);
U.S. Cl.
CPC ...
A61L 24/102 (2013.01); A61F 2/2846 (2013.01); A61F 2/30907 (2013.01); A61K 38/1841 (2013.01); A61K 38/1875 (2013.01); A61L 24/0015 (2013.01); A61L 24/0089 (2013.01); A61L 24/0094 (2013.01); A61L 24/02 (2013.01); A61L 24/06 (2013.01); A61L 24/108 (2013.01); A61B 17/866 (2013.01); A61B 2017/564 (2013.01); A61B 2017/8655 (2013.01); A61F 2/30723 (2013.01); A61F 2/30734 (2013.01); A61F 2/3601 (2013.01); A61F 2002/30736 (2013.01); A61F 2002/30919 (2013.01); A61F 2310/00011 (2013.01); A61L 2300/102 (2013.01); A61L 2300/252 (2013.01); A61L 2300/404 (2013.01); A61L 2300/414 (2013.01); A61L 2400/12 (2013.01); A61L 2430/02 (2013.01);
Abstract

The present invention provides processes for combined applications of making grooves on an implant surface, applying MgO nanoparticles with PMMA cement, restricting the cement movement by PCL nanofiber and tethering biomolecules with PCL nanofiber to enhance mechanical stability and osseointegration of PMMA cement with bone. This is achieved through enhanced osteoconductive properties, roughness, and less viable fracture originating sites at the bone-cement interface. Such combined applications of nanoparticle and nanofiber on the mechanical stability and osseointegration of cemented implant is heretofore unknown, but as provided by the present invention can solve the debonding problem of cemented implant from bone.


Find Patent Forward Citations

Loading…