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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10286013 B1

PDFFull Text
Date of Patent:
May. 14, 2019

Filed:

Oct. 27, 2016

Pancreatic islets of transgenic lea29y animals for treating diabetes

Applicant:

Mwm Biomodels Gmbh, Tiefenbach, DE;

Inventors:

Eckhard Wolf, Vierkirchen, DE;

Nikolai Klymiuk, Hohenkammer, DE;

Lelia Wolf-Van Buerck, Aschheim, DE;

Jochen Seißler, München, DE;

Assignee:

MWM BIOMODELS GMBH, Tiefenbach, DE;

Attorney:

Saliwanchik, Lloyd & Eisenschenk

Primary Examiner:

Scott Long

Assistant Examiner:

Arthur S Leonard

Int. Cl.
CPC ...
A61K 35/39 (2015.01); A01K 67/027 (2006.01); A61K 35/54 (2015.01); C12N 15/85 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 35/39 (2013.01); A01K 67/0275 (2013.01); A61K 35/54 (2013.01); C07K 14/70521 (2013.01); C12N 15/85 (2013.01); C12N 15/8509 (2013.01); A01K 2207/15 (2013.01); A01K 2217/00 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2227/108 (2013.01); A01K 2267/025 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to methods of treating diabetes in a human subject comprising the use of pancreatic islets or of embryonic pancreatic tissue of a transgenic animal, wherein said transgenic animal contains a polynucleotide sequence encoding a CTLA4 peptide-immunoglobulin fusion, preferably LEA29Y, and expresses said CTLA4 peptide-immunoglobulin fusion in a tissue-specific manner in pancreatic islets.

Find Patent Forward Citations

Wolf, Eckhard. (2019). Pancreatic islets of transgenic lea29y animals for treating diabetes (U.S. Patent No. 10286013). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10286013

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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