The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Apr. 27, 2015
Applicants:

Jeffrey D. Rimer, Houston, TX (US);

Jihae Chung, Houston, TX (US);

John Asplin, Chicago, IL (US);

Inventors:

Jeffrey D. Rimer, Houston, TX (US);

Jihae Chung, Houston, TX (US);

John Asplin, Chicago, IL (US);

Assignee:

University of Houston System, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/194 (2006.01); A61K 45/06 (2006.01); C07C 59/245 (2006.01);
U.S. Cl.
CPC ...
A61K 31/194 (2013.01); A61K 45/06 (2013.01); C07C 59/245 (2013.01);
Abstract

In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.


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