The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2019

Filed:

Aug. 04, 2017
Applicants:

Nocimed, Inc., Redwood City, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

James Clayton Peacock, III, San Carlos, CA (US);

John Patrick Claude, Redwood City, CA (US);

Paul Henry Kane, Albuquerque, NM (US);

Jeffrey C. Lotz, San Mateo, CA (US);

Assignees:

Nocimed, Inc., Redwood City, CA (US);

The Regents of the University of California, Oakland, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); A61B 5/00 (2006.01); A61B 5/055 (2006.01); G01R 33/485 (2006.01);
U.S. Cl.
CPC ...
A61B 5/055 (2013.01); A61B 5/4514 (2013.01); A61B 5/4566 (2013.01); A61B 5/4824 (2013.01); A61B 5/748 (2013.01); G01R 33/485 (2013.01); A61B 5/743 (2013.01); A61B 2576/02 (2013.01);
Abstract

An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.


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