The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Aug. 06, 2015
Applicants:

College of Medicine Pochon Cha University Industry-academic Cooperation Foundation, Pocheon, KR;

Institute for Basic Science, Daejeon, KR;

Inventors:

Jin Soo Kim, Seoul, KR;

Dong Youn Hwang, Seongnam, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01); C12Q 1/6881 (2018.01); C12N 5/0735 (2010.01); C07K 14/74 (2006.01); C12N 5/073 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C07K 14/70539 (2013.01); C12N 5/0603 (2013.01); C12N 5/0606 (2013.01); C12Q 1/6881 (2013.01); C12N 2501/50 (2013.01); C12N 2501/70 (2013.01); C12N 2510/00 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present invention relates to a method for producing immune-compatible cells or a cell population which comprises a step of editing one or two alleles of one or more immune-compatible antigen genes by gene deletion or modification in an isolated cell comprising at least one of the immune-compatible antigen genes selected from HLA (human leukocyte antigen)-A, HLA-B and HLA-DR, to immune-compatible cells produced by the method, and to a cell population comprising the immune-compatible cells produced by the method.


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