The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Jun. 01, 2016
Applicant:

Jenkem Technology Co., Ltd. (Beijing), Beijing, CN;

Inventors:

Meina Lin, Beijing, CN;

Xiaomeng Chen, Beijing, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08G 65/333 (2006.01); C08G 65/332 (2006.01); C08G 65/329 (2006.01); C08G 65/331 (2006.01); C08G 65/337 (2006.01); A61K 47/60 (2017.01); A61K 47/69 (2017.01); A61K 9/06 (2006.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
C08G 65/33324 (2013.01); A61K 47/60 (2017.08); A61K 47/6903 (2017.08); C08G 65/329 (2013.01); C08G 65/331 (2013.01); C08G 65/332 (2013.01); C08G 65/337 (2013.01); C08G 65/3322 (2013.01); C08G 65/33306 (2013.01); C08G 65/33331 (2013.01); C08G 65/33337 (2013.01); A61K 9/06 (2013.01); A61K 47/34 (2013.01); C08G 2650/30 (2013.01); C08G 2650/32 (2013.01); C08G 2650/60 (2013.01); C08L 2203/02 (2013.01);
Abstract

The present invention provides an alkynyl multi-arm polyethylene glycol derivative having a structure of a general formula I or general formula X VIII. In the derivative, X1, X2, X3 and X4 are linking groups, F1, F2, F3 and F4 are end groups, the end groups may be the same or may also be different, and are selected from: hydroxy, carboxyl, ester group, amino, alkynyl or the like, at least one of the end groups is alkynyl, and PEG is the same or different —(CHCHO)—, wherein m is an integer ranging from 3 to 250, and l is an integer greater than or equal to 1. The multi-arm polyethylene glycol derivatives have stronger application flexibility, and have good application prospect in aspects such as organic synthesis, medicine synthesis and medical instruments.


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