The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2019
Filed:
Apr. 24, 2015
Applicant:
Albert Einstein College of Medicine, Inc., Bronx, NY (US);
Inventors:
Xingxing Zang, New York, NY (US);
Jordan M. Chinai, Bronx, NY (US);
Murali Janakiram, Brooklyn, NY (US);
Steven C. Almo, Pelham, NY (US);
Andras Fiser, New York, NY (US);
Assignee:
Albert Einstein College of Medicine, Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/70 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70503 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.