The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Dec. 18, 2015
Applicant:

Dh Technologies Development Pte Ltd., Singapore, SG;

Inventor:

Yves Le Blanc, Newmarket, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C07K 14/62 (2006.01); C07K 16/00 (2006.01); G01N 30/06 (2006.01); G01N 30/12 (2006.01); G01N 30/30 (2006.01); G01N 30/72 (2006.01); G01N 30/88 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); G01N 30/06 (2013.01); G01N 30/12 (2013.01); G01N 30/30 (2013.01); G01N 30/72 (2013.01); G01N 30/7233 (2013.01); C07K 16/00 (2013.01); C12N 9/00 (2013.01); G01N 33/68 (2013.01); G01N 2030/067 (2013.01); G01N 2030/8831 (2013.01);
Abstract

Methods and systems are provided herein for on-line preparation of a sample for mass spectrometry. In accordance with various aspects of applicant's teachings, the methods and systems can provide for the reduction of a polypeptide, for example, on a liquid chromatography column and can reduce or eliminate the need to incubate the reducing agent with the polypeptide and/or expose the reduced polypeptide to an alkylating agent.


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