The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Mar. 23, 2017
Applicant:

Nerviano Medical Sciences S.r.l., Milan, IT;

Inventors:

Gabriella Traquandi, Milan, IT;

Maria Gabriella Brasca, Milan, IT;

Roberto D'Alessio, Milan, IT;

Paolo Polucci, Milan, IT;

Fulvia Roletto, Milan, IT;

Anna Vulpetti, Milan, IT;

Paolo Pevarello, Pavia, IT;

Achille Panzeri, Merate, IT;

Francesca Quartieri, Arona, IT;

Ron Ferguson, Casale Litta, IT;

Paola Vianello, Milan, IT;

Daniele Fancelli, Milan, IT;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); C07D 487/04 (2006.01); C07D 401/10 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C07D 231/56 (2006.01); C07D 239/72 (2006.01); A61K 31/519 (2006.01); A61K 31/551 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); C07D 231/56 (2013.01); C07D 239/72 (2013.01); C07D 401/10 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 487/04 (2013.01);
Abstract

Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.


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