The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Feb. 01, 2017
Applicant:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Inventors:

Yat Sun Or, Watertown, MA (US);

Meizhong Jin, Wellesley, MA (US);

Jorden Kass, Belmont, MA (US);

Hui Cao, Belmont, MA (US);

Xuri Gao, Newton, MA (US);

Wei Li, Lexington, MA (US);

Xiaowen Peng, Sudbury, MA (US);

Yao-Ling Qiu, Andover, MA (US);

Assignee:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/10 (2006.01); A61K 31/4178 (2006.01); A61K 31/435 (2006.01); A61K 31/438 (2006.01); A61K 31/46 (2006.01); C07D 221/20 (2006.01); C07D 403/12 (2006.01); C07D 451/02 (2006.01); C07D 451/06 (2006.01); C07D 471/10 (2006.01);
U.S. Cl.
CPC ...
C07D 487/10 (2013.01); A61K 31/4178 (2013.01); A61K 31/435 (2013.01); A61K 31/438 (2013.01); A61K 31/46 (2013.01); C07D 221/20 (2013.01); C07D 403/12 (2013.01); C07D 451/02 (2013.01); C07D 451/06 (2013.01); C07D 471/10 (2013.01);
Abstract

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof:X-A-Y—Z—R  (I)which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.


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