The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2019
Filed:
Feb. 10, 2017
Applicant:
University of Rochester, Rochester, NY (US);
Inventor:
Steven A. Goldman, Webster, NY (US);
Assignee:
University of Rochester, Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); A61K 35/30 (2015.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01); C12N 5/079 (2010.01); G01N 33/50 (2006.01); A01K 67/027 (2006.01); A61K 35/545 (2015.01);
U.S. Cl.
CPC ...
A61K 49/0008 (2013.01); A01K 67/0271 (2013.01); A61K 35/30 (2013.01); A61K 35/545 (2013.01); A61K 45/06 (2013.01); C12N 5/06 (2013.01); C12N 5/0622 (2013.01); G01N 33/50 (2013.01); G01N 33/5085 (2013.01); A01K 2207/12 (2013.01); A01K 2207/15 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0318 (2013.01); G01N 2800/28 (2013.01); G01N 2800/2814 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2835 (2013.01);
Abstract
The present application relates to a non-human mammal model of a human neurodegenerative disorder, methods of producing the non-human mammal model, and methods of using the non-human mammal model to identify agents suitable for treating a neurodegenerative disorder. The present application also relates to methods of treating neurodegenerative disorders and restoring normal brain interstitial potassium levels.