The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

May. 05, 2017
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Qiang Cong, Palo Alto, CA (US);

Sanjeev Gangwar, Foster City, CA (US);

Vangipuram S. Rangan, Pleasant Hill, CA (US);

Mei-Chen Sung, Milpitas, CA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 47/6811 (2017.08); A61K 47/6851 (2017.08); C07K 16/28 (2013.01); C07K 2317/565 (2013.01); C07K 2317/94 (2013.01);
Abstract

The drug component of an antibody-drug conjugate having a structure according to formula (II), where Ab, m, n, R, R, R, R, and Rare as defined in the application, exhibits unexpectedly improved stability.


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