The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2019
Filed:
Dec. 03, 2013
Unity Biotechnology, Inc., San Francisco, CA (US);
Kythera Biopharmaceuticals, Inc., Calabasas, CA;
Buck Institute for Research on Aging, Novato, CA (US);
Alain Philippe Vasserot, Carlsbad, CA (US);
Serge Lichtsteiner, Westlake Village, CA (US);
Judith Campisi, Berkeley, CA (US);
UNITY BIOTECHNOLOGY, INC., Brisbane, CA (US);
BUCK INSTITUTE FOR RESEARCH ON AGING, Novato, CA (US);
KYTHERA BIOPHARMACEUTICALS, INC., Westlake Village, CA (US);
Abstract
Provided herein are immunogenic compositions (vaccines) and methods for immunizing a subject with the immunogenic compositions for inducing an adaptive immune response directed specifically against senescent cells for treatment and prophylaxis of age-related diseases and disorders, and other diseases and disorders associated with or exacerbated by the presence of senescent cells. The immunogenic compositions provided herein comprise at least one or more senescent cell-associated antigens, polynucleotides encoding senescent cell-associated antigens, and recombinant expression vectors comprising the polynucleotides for use in administering to a subject in need thereof.