The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Mar. 10, 2014
Applicant:

Healthpartners Research & Education, Minneapolis, MN (US);

Inventor:

William H. Frey, II, White Bear Lake, MN (US);

Assignee:

HealthPartners Research & Education, Minneapolis, MN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); A61K 9/00 (2006.01); A61K 38/18 (2006.01); A61K 38/51 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 9/0043 (2013.01); A61K 38/1883 (2013.01); A61K 38/51 (2013.01); A61K 45/06 (2013.01); C12Y 402/02001 (2013.01);
Abstract

Methods for delivering an effective amount of insulin to the central nervous system to treat Social Communication Disorder while minimizing systemic exposure to the administered insulin. The present invention provides these advantages by administering at least an effective amount of insulin and/or pharmaceutical composition(s) thereof, to the upper third of the nasal cavity, thereby bypassing the blood-brain barrier and delivering an effective amount of insulin and/or pharmaceutical compound(s) thereof directly to the CNS. Further methods comprise administering an at least an effective amount of therapeutic agents to the amniotic fluid surrounding a fetus with a treatable neurologic agent or a preventable neurologic condition. For example, administering the at least effective amount of insulin to the amniotic fluid of a fetus with a mother diagnosed with gestational diabetes may prevent the fetus from developing Social Communication Disorder or autism.


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