The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2019

Filed:

Feb. 06, 2018
Applicant:

Kenichiro Hasumi, Tokyo, JP;

Inventor:

Kenichiro Hasumi, Tokyo, JP;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 45/00 (2006.01); A61K 47/00 (2006.01); A61K 35/15 (2015.01); A61K 39/395 (2006.01); C12N 5/0784 (2010.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C07K 16/24 (2006.01); A61K 38/19 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 35/17 (2013.01); A61K 38/19 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); C07K 16/241 (2013.01); C12N 5/0638 (2013.01); C12N 5/0639 (2013.01); A61K 2039/5154 (2013.01); C12N 2501/25 (2013.01);
Abstract

The invention relates to therapy and methods of applying the therapy to a patient. The invention includes the introduction of immature dendritic cells into the patient and the introduction of anti-TNF antibody into the patient. The immature dendritic cells are introduced intratumorally and/or through vessel and the anti-TNF antibody is introduced intratumorally and/or through vessel and/or subcutaneously. The immature dendritic cells can be formed by collecting monocyte cells from the patient and culturing the cells in a culture medium. The invention can be effective to regress, reduce or eliminate tumor cells in tumor tissue of the patients, including metastasized tumors. Further, the treatment of the invention is effective in the absence of conventional therapy, such as radiotherapy and chemotherapy.


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